80 results
Clinical Features and Vascular Territories of Stroke
Anterior circulation—anterior cerebral artery (ACA) - Contralateral leg weakness
Anterior circulation—middle
loss, field cut, aphasia ... MCA) or neglect, apraxia ... without cortical signs ... deviation and/or ataxia ... deficits and/or ataxia
Clinical features of focal cortical brain lesions in a right-handed individual

Frontal, either:  
Intellectual impairment, 
Personality
left: Broca's aphasia ... Acalculia, Alexia ... right: Dressing apraxia ... left: Limb apraxia ... Localization #Symptoms #Signs
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... chromosome 21) Signs ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
spinal cord - Signs ... and Symptoms • Ataxia ... (early sign) ... weakness (late sign ... dexterity loss (early signs
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... Inflammatory bowel disease ... , Malnutrition Signs ... Optic neuropathy, Ataxia ... Deficiency #diagnosis #signs
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Dose-dependent tremor, ataxia ... dizziness, diplopia, ataxia ... #SideEffects #Pathophysiology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... , Deafness Signs ... Psychosis/dementia, Ataxia ... Hypothyroid #Features #Signs
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
confusion - Ataxia ... #Pharmacology #pathophysiology
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Haemolytic anaemia, ataxia ... differential #diagnosis #signs