17 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... #Pharmacology #Pathophysiology ... Mechanisms #DOAC #Hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
clotting factor deficiency ... Patient has a factor deficiency ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Diagnosis Framework Hematologic ... Defects • OTC deficiency ... (XLR) • Deficiency ... Differential #Diagnosis #Pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... Causes of Thiamine Deficiency ... production • Deficiency ... Ophthalmoplegia - Ataxia ... beriberi #nutrition #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Protein S deficiency ... - Protein C deficiency ... - Antithrombin deficiency ... Venous #Arterial #pathophysiology ... #hematology #differential
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
CNS: Tremors, Ataxia ... Constipation - MSK ... Syndrome #diagnosis #pathophysiology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
effects including ataxia ... with vitamin B12 deficiency ... #Pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Protein C & S deficiency ... , ATIII deficiency ... anti-coagulation • Hematologic ... Occlusion #CRAO #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
hypothyroidism • Zinc deficiency ... • Vitamin C deficiency ... Pernicious anemia/B12 deficiency ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis