39 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Reactive: • Anemia/blood ... loss (Fe deficiency ... Differential #Diagnosis #causes ... #Platelets #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Causes include : ... Pre-analytical cause ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... #differential #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Microcytic" • Iron deficiency ... disease, Acute blood ... , Folate deficiency ... differential #diagnosis #causes ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... • Dietary Deficiency ... B12 and Folate Deficiency ... #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... Pre-analytical cause ... e.g. heparin ... #differential #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... RBC>13 • Iron Deficiency ... Blood Loss, Occult ... Malabsorption, Dietary Deficiency ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... thrombopoietin deficiency ... Treat primary cause ... #treatment #management ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Protein S deficiency ... - Protein C deficiency ... Hyperhomocysteinemia - Heparin-induced ... coagulation and other causes ... pathophysiology #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... necrosis) • VIT K deficiency ... Cholesterol emboli • Septic ... Differential #Diagnosis #hematology ... #rheumatology #