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diagnosis differential anemia intravascular product rheumatology transfusion treatment aflp alkaline alp aplastic basophilia basophils centralretinalartery cirrhosis coagulation comparison crao dermatology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... during an allergic reaction ... Or Inflammatory Reactions ... : • Iron deficiency ... #hematology #basophils
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
marrow disease - DIC ... necrosis) • VIT K deficiency ... Purpura Fulminans (DIC ... fever • Drug reactions ... Differential #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation (DIC ... G6PD deficiency) ... Extravascular #Causes ... differential #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... thrombopoietin deficiency ... #treatment #management ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... recipients w/ IgA deficiency ... Causes purpura & ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... recipients w/ IgA deficiency ... Causes purpura & ... Transfusions #diagnosis #management ... #hematology #reactions
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... of high parity blood ... donor • Pathophysiology ... without other cause ... #hematology #diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Protein C & S deficiency ... , ATIII deficiency ... anti-coagulation • Hematologic ... retinal edema caused ... Occlusion #CRAO #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... rapidly develops (DIC ... Liver #Pregnancy #hepatology ... #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• blood collection ... with EDTA Pathophysiology ... ) - Waddling gait ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
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