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diagnosis differential anemia management algorithm causes atlas classification elevatedmcv key macrocytosis microscopy morphologic product reactions workup alkaline alp aplastic apml
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology ... disease, McLeod blood ... #Morphology #differential ... #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... / Normochromic RBCs ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... coagulopathy (DIC) #RBC ... #Morphology #Atlas ... #differential #hematology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... cell, Other RBC ... #RedBloodCell #Morphology ... Microscopy #Pathology #Hematology
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... Tests: • MCV/RBC ... - RBC ↓ in proportion ... carrying component of blood ... Fe #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
' nucleotidase deficiency ... other reproducible morphologic ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... Algorithm #workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Algorithm Normal Blood ... Neutrophils - Low RBC ... • Dietary Deficiency ... Pernicious Anemia RBCs ... Algorithm #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
- Fe/TlBC, MCV/RBC ... >13 • Iron Deficiency ... Causes: Chronic Blood ... Malabsorption, Dietary Deficiency ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... deficiencies: Iron deficiency ... anemia, Intrinsic RBC ... cell anemia, G6PD deficiency ... Production #Index #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron deficiency ... disease, Acute blood ... , Folate deficiency ... EricsMedicalLectures/ #anemia #morphologic ... diagnosis #causes #hematology
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