92 results
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
dysfunction (e.g. gait ... ataxia - usually ... upper limb) • Nutritional ... risk factor for nutritional ... Management #neurology #nutrition
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Infiltration: • Hematologic ... and non-hematologic ... Myelodysplasia Nutritional ... deficiency: • ... Algorithm #Causes #Hematology
Causes of Gait Disturbance - Differential Diagnosis Algorithm
Sporadic
 • Vascular
 • Infection
 • Toxic
 • Nutrition
Causes of Gait Disturbance ... • Toxic • Nutrition ... Childhood Catalytic Deficiency ... Childhood Catalytic Deficiency ... Niemann-Pick Disease #Gait
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... Total parenteral nutrition ... /jejunal nutrition ... Optic neuropathy, Ataxia ... drkeithsiau #Copper #Deficiency
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Thiamine (B1) Deficiency ... dysfunction - Dietary deficiency ... dysfunction and gait ... ataxia is only ... #Thiamine #B1 #Deficiency
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Diseases: • GATA2 deficiency ... Antibody-mediated hemolysis Nutritional ... B12 • Folate deficiency ... Differential #Diagnosis #Hematology
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
and/or Folate Deficiency ... to diagnosis deficiency ... levels will be deficient ... #Diagnosis #Nutrition ... #Hematology #ComparisonTable
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
B12 and Folate Deficiency ... • B12 Deficiency ... elevated • Folate Deficiency ... #MMA #folate #deficiency ... VitaminB12 #diagnosis #hematology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... Haemolytic anaemia, ataxia ... #Vitamins #Deficiency ... signs #symptoms #nutrition
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Non malignant hematologic ... states • Non-hematologic ... malignancy • Iron deficiency ... Algorithm #Causes #Hematology