8 results
diagnosis differential management algorithm extravascular hemolysis intravascular rheumatology antibody arteritis common criteria cvid erythematosus gca giantcell immunodeficiency immunology lupus monoclonal
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... (e.g. primary cold ... differential #diagnosis #hematology ... #anemia
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... Hemolytic Anemia ... 2) LOOK FOR a cause ... → Systematic screening ... #Hemolytic #Anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Warm AIHA • Cold ... AIHA • Alloimmune ... anemia • ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... thalassemia, S Lepore • Basophilic ... Agglutination - Cold ... elliptocytosis, autoimmune ... Algorithm #workup #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
: Pneumonia • Autoimmune ... hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... #immunology #hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Diagnostic Criteria - Systemic ... SEROSITIS - RENAL - NEUROLOGIC ... - HEMOLYTIC ANEMIA ... reference range (or 2-fold ... #Rheumatology #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
, neurologic, and ... sx + signs/sx of ... complaints- anemia ... identifies 85 to 95% of cases ... GCA #Temporal #Signs
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