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management differential nephrology syndrome classification oncology rheumatology hepatology lupus sle syndromes algorithm bacilliformis bartonella bells blood bloodsmear borrelia cancer chagas
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Simplified Approach to Acute ... cases are caused ... , RBCs, casts, crystals ... #simplified #workup ... #diagnosis #nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... and Diagnosis Algorithm ... repeat testing • Acute ... proteinuria, RBC casts ... if cause not identified
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... Light chain (LC) cast ... • Hematologic ... malignancies Treatment ... #Differential #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... PLT in selected cases ... (CVID, WAS), (neurologic ... #Causes #Workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... decrease in most cases ... schistocytes, nucleated RBCs ... hematuria (without casts ... #Workup #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... normal in mild cases ... - Acute Bleeding ... #hematology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... hypergammaglobulinemia, ↑ acute ... maintenance with GCs ... #phenotypes #workup ... #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... Nodular → Mular DIAGNOSIS ... TREATMENT: ​• Acute ... #Oroya #Fever #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... have fever - ACS ... , AKI, acute limb ... Syndrome #TLS #diagnosis ... #management #hematology
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