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diagnosis hepatology management nephrology aki liver aclf alcoholic autoimmune causes chronic cirrhosis classification differential dili druginduced gastroenterology hepatorenal hrs kidney
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... underlying liver disease ... Infections Alcohol-Associated ... Hepatitis (AAH) ... Drug-Induced Liver Injury
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... Dehydration • Heart failure ... syndrome) • Liver failure ... - Post-infectious ... #Kidney #Injury
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... HEMODYNAMIC • Cardiac failure ... • Primary GNs: Disease ... Post-infectious ... Tubular Injury/
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... to acute liver ... failure ... pattern of liver injury ... regarding need for treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... Hepatocellular: Viral infections ... Alcohol-related liver disease ... dechallenge • Acute
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Screen for infection ... injury with serum ... - Concomitant diseases ... - Multiorgan failure
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... severe alcoholic hepatitis ... , or acute liver ... failure ... Treatment Overview
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