13 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... months without treatment ... disease, liver ... Kidney Failure
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Torsemide) • Acute ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... disease, Hepatic ... dechallenge • Acute ... #hepatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... lesions, meninges, kidneys ... hypergammaglobulinemia, ↑ acute ... #diagnosis #management ... #rheumatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... failure ... regarding need for treatment ... #Hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Heart, lung, and kidney ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Algorithm Assess ... : - Acute kidney ... - Concomitant diseases ... - Multiorgan failure ... #Algorithm #hepatology
Pulmonary Histoplasmosis
Quick Facts on Histoplasma capsulatum:
 • Dimorphic fungi, in yeast phase within the body
 •
valleys • Lives ... , PCR Treatment ... Duration depends on acute ... for respiratory failure ... capsulatum #diagnosis #management
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
disease: cirrhosis ... hepatitis, or acute ... liver failure ... Treatment Overview ... #Nephrology #Diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... hypoTN, renal failure ... eruptions, diarrhea, liver ... Transfusion #diagnosis #management ... #hematology #reactions