7 results
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... blood is a liquid ... Blood saves lives ... unnecessary and cause ... #Thresholds #Hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... - Allergic ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies bind ... - Red blood cell ... destruction after transfusion ... with mismatched blood ... Diagnosis #Reactions #Table
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... • Allergic reaction ... Causes purpura & ... TRALI): Leading cause ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... of high parity blood ... without other cause ... #Reactions #hematology ... diagnosis #comparison #table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... lgE causes mast-cell ... lgM antibodies bind ... Examples: Acute transfusion ... #table #classification
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... CANDLE syndrome - Allergic ... neutrophils in the blood ... Syndrome #diagnosis #dermatology ... #oncology