23 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Autoimmune Hemolytic anemia ... Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... #Allergic #Reactions ... #Types #Classification
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
reactions Type ... Days (Hemolytic Anemia ... hypersensitivity #reactions ... #Types #Classification ... #Allergy #Diagnosis
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... reactionType ... reactionType ... reactionType ... #Types #Classification
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... Antibodies that bind ... reaction. ... complexes bind ... histamine) into the blood
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies bind ... - Red blood cell ... with mismatched blood ... #Classification ... #Diagnosis #Reactions
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... #types #allergy ... #table #classification
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... and Treatment Types ... drug reaction - ... cell-mediated in > 90% of cases ... #Types #Diagnosis
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
for Hemolytic Anemia ... • Transfusion reactions ... #Hemolytic #Anemia ... #classification ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hematologic: Acute blood ... hemolysis, deficiency anemia ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... released during an allergic ... reaction or asthma ... Or Inflammatory Reactions ... #hematology #basophils