29 results
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... reactionType ... reactionType ... reactionType ... #Types #Classification
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... Antibodies that bind ... reaction. ... complexes bind ... histamine) into the blood
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies bind ... - Red blood cell ... with mismatched blood ... #Classification ... #Diagnosis #Reactions
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... #types #allergy ... #table #classification
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... and Treatment Types ... drug reaction - ... cell-mediated in > 90% of cases ... #Types #Diagnosis
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... the total white blood ... released during an allergic ... reaction or asthma ... #hematology #basophils
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... are asthma, allergy ... , drug reaction, ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hematologic: Acute blood ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... • Transfusion reactions ... Hemolytic #Anemia #Differential ... #classification ... #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Pager Summary Type ... type and detects ... Product Types: ... - Allergic ... Causes purpura &