24 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... /Quantity: • Primary ... fever • Drug reactions ... #hematology #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... allergy, drug reaction ... (eg, skin or esophageal ... #Differential #diagnosis ... #hematology #eosinophilia
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
thickening Signs and Symptoms ... Hepatic: PBC (primary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Cranial nerve lesions ... , Aortic valve lesions ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
symptoms by days ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... Sweet #Syndrome #diagnosis ... #dermatology #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... meningitis), MCC CNS symptoms ... test (this is a skin ... management #signs #symptoms ... #rheumatology #
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
and duration of symptoms ... lesions - Wheals ... angioedema Other symptoms ... Cold #Urticaria #diagnosis ... #rheumatology #
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... Primary (essential ... Cryofibrinogenemia Diagnosis ... #rheumatology # ... hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
disease, drug reactions ... with GCA or as primary ... Rash, arthritis Primary ... • Progressive symptoms ... #Rheumatology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
constitutional symptoms ... Anemia, and Bone lesions ... cells < 10% • Urinary ... #Significance #hematology ... #diagnosis #oncology