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rheumatology differential dermatology management systemic erythematosus lupus sle syndrome syphilis vasculitis workup algorithm arteritis arthritis autoimmune behcet biliary bonetumors bony
Stages of Syphilis Early Primary: • Painless chancre • Regional lymphadenopathy Early Secondary: • Fever, malaise • Rash
Syphilis Early Primary ... testing • No symptoms ... Gummatous • Nodular lesions ... in bone, skin, ... #signs #diagnosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
thickening Signs ... and Symptoms: ... Hepatic: PBC (primary ... #diagnosis #signs ... #symptoms #testing
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
allergy, drug reaction ... organ-specific signs ... , skin or esophageal ... #Differential #diagnosis ... #hematology #eosinophilia
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Cranial nerve lesions ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... meningitis), MCC CNS symptoms ... test (this is a skin ... #management #signs ... #symptoms #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... symptoms by days ... , breast CA - Hematologic ... Sweet #Syndrome #diagnosis
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
more common than primary ... differently from primary ... Signs/Symptoms: ... Interrupted periosteal reaction ... Malignant #Radiology #Diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... lesions that result ... /Quantity: • Primary ... fever • Drug reactions
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... failure PBC Signs ... and Symptoms: ... Examination: • Skin ... #workup #hepatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
disease, drug reactions ... purpura: Strong sign ... with GCA or as primary ... Rash, arthritis Primary ... #Rheumatology
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