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hematology differential algorithm causes management workup hemolytic oncology classification hemolysis comparison table clinical teg treatment allergy blood deficiency hypersensitivity interpretation
Algorithm for the Evaluation and Management of Transfusion Reactions This algorithm was developed by Dr. Eric Madden,
Management of Transfusion ... Reactions This ... #Transfusion #Reactions ... #Algorithm #Diagnosis ... #Management #Hematology
Estimated Incidence of Transfusion Reactions Graphical Depiction of transfusion reactions ordered from most highest to lowest incidence. #Diagnosis
Reactions Graphical ... Depiction of transfusion ... reactions ordered ... #Diagnosis #Blood ... #Reactions #Events
Transfusion Reactions - Summary Cheatsheet • Hemolytic Reaction • Febrile Reactions • Transfusion Related Acute Lung
Transfusion Reactions ... Cheatsheet • Hemolytic Reaction ... • Febrile Reactions ... #Reactions #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... #diagnosis #management ... #hematology #reactions
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... HUS) • Other: Transfusion ... reaction, Paroxysmal ... reaction • Intrinsic ... #hematology #anemia
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... Reaction (AHTR) ... #diagnosis #management ... #hematology #reactions
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... prosthetic valve • Transfusion ... reactions ex. ... classification #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... AIHA, Cold AIHA, Transfusion ... reactions, Drug-associated ... Defects: Sickle cell anemia ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... plasma volume transfusion ... #Reactions #hematology ... #diagnosis #comparison
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
hypersensitivity reactions ... Days (Hemolytic Anemia ... Rash, SJS) - Amelia ... hypersensitivity #reactions ... Classification #Allergy #Diagnosis
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