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differential lupus sle symptoms classification ana antinuclear associations bullous compared cryoglobulinemia cryoglobulins dermatology druginduced erythemas hematology inflammatory management mimickers monoclonal
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... • Scleroderma (Systemic ... Polymerase Ill • ANCA Vasculitis ... diagnosis #associations ... #table
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... #Lupus #Erythematosus ... #Diagnosis #autoantibodies ... #signs #symptoms ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Butterfly rash, Vasculitis ... #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
heliotrope, shawl sign ... Associated Features: Diagnosis ... #differential #diagnosis ... #comparison #rheumatology ... #table
Pemphigus Vulgaris vs Bullous Pemphigoid - Comparison Table Pemphigus Vulgaris • Epidemiology: Average age 40-60 • Time
Bullous Pemphigoid - Comparison ... Table Pemphigus ... ruptured • Nikolsky sign ... • Antibodies: Autoantibodies ... #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... ischemia - Skin: erythematous ... lupus erythematosus ... purpura: strong sign ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... Differential Diagnosis ... Non-autoimmune rheumatologic ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... activity that bind ... Labs/Diagnosis: ... lupus erythematosus ... classification #rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
associated with rheumatologic ... presentation of systemic ... lupus erythematosus ... #Presentation #comparison ... #Table #Diagnosis
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 Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
syndrome • CVST • Bing-Neel ... Autoimmunity: • -MM/WM: Vasculitis ... ) Autoantibodies ... Paraproteinemias #Hematology ... #Differential #Diagnosis
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