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differential liver transaminitis chemistry elevation functiontest hematology hepatitis interpretation pancytopenia patterns rvalue
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs ... ) vs Indirect (Hemolytic ... #FunctionTest #LFTs ... Transaminitis #diagnosis ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... Gilbert's syndrome • Hemolysis ... liver #chemistry #diagnosis ... #differential #Hepatology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Algorithm • 12 ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... #Algorithm #hematology ... #workup
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular ... Gilbert's syndrome • Hemolysis ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... #algorithm #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... 2-5x normal - Hemolysis ... AST:ALT = 1 ... #hepatology #LFTs ... #differential #diagnosis
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