22 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... awaiting confirmatory testing ... Microangiopathy #thrombocytopenic ... #Comparison #Diagnosis ... #Table #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... tests, Low Platelets ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... tests, Low Platelets ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... smear, HIV/HCV testing ... : INR/PT, aPTT(liver ... #Workup #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
enzymes, and Low ... features: Hemolysis, Thrombocytopenia ... Disease #Pregnancy #hepatology ... #differential # ... diagnosis #icp #
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Diagnosis Poor ... NG drainage - Diarrhea ... type 4) - Salt wasting ... #Diagnosis #Low ... #Potassium #Table
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... POCUS #radiology #differential ... #diagnosis #comparison ... #table #appearance ... #hepatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... chain IIA • Thrombocytopenia ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
1 or Type 3) — differentiate ... Gplb receptor • Thrombcytopenia ... considered first-line testing ... #hemepath #differential ... #diagnosis #Aggregometry
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
losses - Chronic diarrhea ... Familial renal Mg wasting ... Hypomagnesemia #Differential ... #Diagnosis #Low ... #Magnesium #Table