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diagnosis differential hepatology dermatology liver management systemic anemia generalized hepatitis polycythemia pruritus alcoholic approach common cryoglobulinemia cryoglobulins cvid drug druginduced
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
dose dependent injury ... presentation • Chronic ... symptoms of liver disease ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... for alternative causes ... Alcohol-related liver disease ... e.g. ascites), Chronic ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... > 2 • NASH, Chronic ... : > 3 • Chronic ... #hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... #Anemia #MCV #Classification ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Differential Diagnosis Algorithm ... • Burns • Diarrhea ... Sleep Apnea • Chronic ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... RBCs on Smear • Chronic ... Disease • Marrow ... Non-lmmune #Anemia #Classification ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Systemic and Primary Causes ... Creatinine & BUN: • Chronic ... Pruritus #primary #secondary ... #causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... discoloration) • Chronic ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... Autoimmunity • Chronic ... • Infectious diarrhea ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... normal/high - Chronic ... causes: Many of ... As with many disease
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