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diagnosis hepatology differential blood dili hematology product reactions aclf aih aki alcoholic autoimmune causes chronic cirrhosis drug druginduced failure idiosyncratic
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... disease, liver ... Injury (DILI) ... Viral Hepatitis ... Cirrhosis #Hepatology #gastroenterology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... , Acute biliary ... #Injury #Differential ... #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Liver Injury: ... Liver Injury: ... #injury #hepatitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... disease 6-9 mo ... differential #Diagnosis #Management ... #gastroenterology ... #algorithm #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ... dechallenge • Acute ... • Autoimmune hepatitis ... #Algorithm #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... to acute liver ... hepatocellular pattern of liver ... injury, though ... (eg Viral) Management
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... disease, ? ... Medications → Stop meds
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... kidney injury with ... - Concomitant diseases ... #Management #Algorithm
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Lung Injury (TRALI ... cutaneous eruptions, diarrhea ... , liver abnormalities ... Transfusion #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Lung Injury (TRALI ... cutaneous eruptions, diarrhea ... , liver abnormalities ... Transfusions #diagnosis #management
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