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diagnosis differential hepatology causes management hepatitis injury nephrology thrombocytosis aclf aih anemia autoimmune cellulitis chemistry cirrhosis ckd classification clinical dermatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... disease, liver ... Failure Infections Alcohol-Associated ... #Chronic #Liver
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... HSV • Toxic: Alcohol ... Syndrome, Celiac Disease ... Medication, Pregnancy, Alcoholic ... #algorithm #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Infectious: • Acute ... or Chronic Inflammatory ... disorders • Celiac disease ... effect following treatment
Hypophosphatemia - Differential Diagnosis Algorithm Transcellular Shift • Recovery From DKA • Refeeding Syndrome • Acute Respiratory
Differential Diagnosis Algorithm ... Refeeding Syndrome • Acute ... • Small bowel diarrhea ... Alcoholism Decreased ... Inflammatory Bowel Disease
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... liver disease, ... dechallenge • Acute ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... ALT Ratios: • Alcoholic ... liver disease: ... #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic ... Differential #Diagnosis #Algorithm
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
kidney disease, ... Acute blood loss ... use, Liver disease ... independent of alcohol ... diagnosis #causes #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... ALT Ratios: • Alcoholic ... liver disease: ... > 2 • NASH, Chronic ... injury: > 3 • Chronic
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Differential Diagnosis Algorithm ... Renal Failure • Liver ... Neoplastic / Hematologic ... Obstructive Pulmonary Disease ... Alcohol) • Drug
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