9 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... disease, liver ... Failure Infections Alcohol-Associated ... gastroenterology #management
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... disease, ? ... #management
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
disease: cirrhosis ... , severe alcoholic ... hepatitis, or acute ... Treatment Overview ... insult (e.g., alcohol
Treatment of Alcohol Use Disorder

Treatment options for AUD include psychosocial treatment and medications. Individualize based on
Treatment of Alcohol ... disease or using ... Can be used in liver ... CarolynAChan #Alcohol ... #Management #AUD
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... liver disease, ... dechallenge • Acute
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... stores in the liver ... beta-oxidation in the liver ... #differential #algorithm ... #management #treatment
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... : - Acute kidney ... - Concomitant diseases ... HCV, DILI, HCC, acute
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
What is it: • Aka ... oxoprolinase • Acquired disease ... • Concomitant acute ... deficiency) • Liver ... Oxoprolinuria #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
tongue), abd pain, diarrhea ... to IBD, celiac disease ... , intestinal), alcohol ... Check for IF ab Treatment ... Deficiency #diagnosis #management