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hematology differential causes workup classification management oncology pancytopenia approach bleeding common cvid hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology lymphoma macrocytic macrocytosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
of Bleeding / Bruising ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... Sequestration Disordered ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... • Small Bowel Disorder ... #Macrocytosis #elevatedMCV ... #Hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... chronic kidney disease ... Probable bone marrow disorder ... Underproduction #Algorithm ... #hematology #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Disease • Marrow ... #Algorithm #Causes ... #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... Systemic #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... Consider RBC membrane disorder ... #hematology #testing
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption ... Disorders 1. ... Acquired Aplastic Anemia ... Metastatic Disease ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption ... Disorders 1. ... Acquired Aplastic Anemia ... Metastatic Disease ... #Algorithm #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... late adulthood • Diagnosis ... • Infectious diarrhea ... autoimmune hemolytic anemia ... conditions Diagnosis
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