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diagnosis management blood product reactions cvid differential essential et gammopathy hemeonc hemophagocytic hodgkins hypogammaglobulinemia immunology lymphohistiocytosis lymphoma lymphomas lymphoproliferative mgrs
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... disorder with hypogammaglobulinemia ... • Infectious diarrhea ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Differential Diagnosis Algorithm ... B-Cell ~90% • Low ... #Classification ... pathophysiology #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... ) Classification ... Blood Count - Low ... may be high or low ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... : - Common in ... Low/absent NK-cell ... malignancy, autoimmune disorder ... Diagnosis #Management #Hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
(FNHTR): Most common ... donors (due to anti-HLA ... cutaneous eruptions, diarrhea ... Hypothermia: Due to low ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... donors (due to anti-HLA ... cutaneous eruptions, diarrhea ... Hypothermia: Due to low ... diagnosis #management #hematology
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... or plasma cell disorder ... • More common ... guide subtype classification ... Damages Kidneys • Low
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... thrombocytosis, only other commonly ... hemoproliferative disorder ... • Treatment algorithms ... appropriate only for low
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