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diagnosis leukemia chronic differential lymphocytic management workup blood causes cell child classification criteria disorders gammopathy hemeonc hemophagocytic hodgkins limping lymphohistiocytosis
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders - Markers ... CD13, CD33, CD34, HLA-DR ... ) - PAS, TdT Lymphadenopathy ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... Phosphorus CLL ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Hepatomegaly, Lymphadenopathy ... : ↑↑ ferritin, Anemia ... d-dimer, ↓ NK cell ... (affecting 2 2 cell ... Lymphohistiocytosis #diagnosis #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
RED FLAGS - In all ... are specific markers ... pallor, bruising, lymphadenopathy ... neurology, back pain Haematology ... #Limping #NWB #Algorithm
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... ITP • SLE • CLL ... Alloimmune • anti-HLA ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
early symptoms • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
) Asymptomatic lymphadenopathy ... 5) Symptoms of anemia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Presentation: • Lymphadenopathy ... Weight loss • Anemia ... (Inflammatory marker ... classification #hematology ... #oncology #management
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... hyperviscosity, lymphadenopathy ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
MM, the plasma cell ... X-Ray Imaging: • Marked ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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