12 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Side Effects: Hypomagnesemia ... , diarrhea, nausea ... ); nausea, vomiting ... constipation, diarrhea ... #pharmacology #table
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
losses - Chronic diarrhea ... - Hypokalemia ... Differential #Diagnosis #Low ... #Magnesium #Table ... Classification #Causes
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Differential Diagnosis Algorithm ... Urine Mg < 10g • Diarrhea ... Diuretics • Hypercalcemia-PTH ... #Magnesium #Low
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
NG drainage - Diarrhea ... - Polyuria - Hypomagnesemia ... Differential #Diagnosis #Low ... #Potassium #Table ... Classification #Causes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Gl tract loss (Diarrhea ... #causes #potassium ... #low #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
water loss, Serum Sodium ... mannitol, glucosuria Low ... loss • Watery Diarrhea ... Hypernatremia #Nephrology ... #Causes
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... Laxative use • Diarrhea ... consumption • Low ... differential #potassium #nephrology ... #low
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... alkalosis • Normal/low ... Gitelman syndrome, Hypomagnesemia ... the indicated causes ... #nephrology #differential
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table ... #sodium #nephrology
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Nephropathies, Vomiting, Diarrhea ... polydipsia • Hypervolemia ... #diagnosis #causes ... #nephrology #sodium ... #low