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management algorithm differential oncology disorders hepatology reactions syndrome 1 cdi cdiff chronic cll clostridioides clostridium dermatology difficile gammopathy gastroenterology hemophagocytic
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
genes and gene products ... Workup: • Full Blood ... Treatment • Early ... #diagnosis #classification ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Hodgkin, T-cell lymphoma ... , B-cell lymphoma ... Unknown cause Treatment ... #management #treatment
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Responsive to Treatment ... Treated Like Acute ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... : Acute blood loss ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... #Differential #Diagnosis
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... and Differential Diagnosis ... Algorithm Acute ... CD13, CD33, CD34, HLA-DR ... #Disorders #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... cutaneous eruptions, diarrhea ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... or acute leukemia ... workup #oncology #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... cutaneous eruptions, diarrhea ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... PBC, PSC, IgG4, HLH ... cell lung CA, lymphoma ... intestines, white blood ... #differential #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
on ABx) → Acute ... Diarrhea (>3 BM ... /d) ± blood/mucus ... Dehydrogenase (↑Sens) - produced ... #management #treatment
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