13 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presents as an acute ... Diagnosis via genetic ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Algorithm for the Evaluation of Acute Diarrhea (< 7 days)
Are the following present?
   1.
Evaluation of Acute ... Ova and parasite ... Bloody diarrhea, ... #Diarrhea #management ... algorithm #workup #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Auto-amplification loop Diagnosis ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... cutaneous eruptions, diarrhea ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... Fibrin degradation products ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
genes and gene products ... Hodgkin Lymphoma Treatment ... #classification ... #hematology #oncology ... #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... cutaneous eruptions, diarrhea ... Blood products contain ... #diagnosis #management ... #hematology #reactions
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
on ABx) → Acute ... Diarrhea (>3 BM ... /d) ± blood/mucus ... Dehydrogenase (↑Sens) - produced ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... ABO incompatible blood ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
hepatitis, or acute ... casts, protein, or blood ... Classification: ... Treatment Overview ... Hepatorenal #Syndrome #Hepatology