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diagnosis differential blood management product reactions ttp anemia bleeding bruising disorders hemolytic hus mds microangiopathy myelodysplasia myelodysplastic nonpalpable oncology palpable
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... test, ANA (e.g., SLE ... or if a primary hematologic ... #Workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Thrombocytopenia ... Splenomegaly - CTD (SLE ... Associated - SLE ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Autoimmune • ITP • SLE ... Heart Valve) #Thrombocytopenia ... #Causes #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Thrombocytopenia ... Sequestration Disordered Platelet ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... genotypes): SS, SC, SE ... with or without platelet ... Schistocytes, thrombocytopenia ... #workup #hematology
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... triad of MAHA + thrombocytopenia ... Cr>2.3 & platelets ... catastrophic APS, SRC, SLE ... Microangiopathy #TMAs #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... hemostasis: - Thrombocytopenia ... - Abnormal platelet ... deficiency Work ... #Causes #dermatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... intravascular hemolysis Platelet ... and decreased platelet ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... Workup: • Complete ... Syndromes #diagnosis #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... some time, let’s see ... you’ll do a good workup ... #workup #hematology
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