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diagnosis differential hematology thrombocytopenia ana anca anemia antibody antineutrophil antinuclear antiphospholipid apls classification diseases disorders glomerulonephritis hemolytic hypercoagulable petechiae petechial
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP • SLE ... Alloimmune • anti-HLA antibodies ... HUS • DIC • Vasculitis ... #Causes #Hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... in drug-induced SLE ... ANCA-Associated Vasculitis ... #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Purpura Anti-GBM antibodies ... Glomerulonephritis #Vasculitis ... #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... (lupus, RA, Sjogren's ... deficiency Work ... #Causes #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... practices that could cause ... test, ANA (e.g., SLE ... anti-phospholipid antibodies ... #Workup #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... such as systemic lupus ... C-ANCA) pattern: antibodies ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... genotypes): SS, SC, SE ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... #workup #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup ... Algorithm INDICATIONS ... maternal chromosomal causes ... excluded Testing: • Lupus ... #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... some time, let’s see ... about secondary causes ... #workup #hematology
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