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diagnosis rheumatology management druginduced polycythemia vasculitis classification dermatology dil erythematosus erythrocytosis glomerulonephritis hypernatremia nephrology petechiae petechial physicalexam progressive rapidly rash
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... in >90% - Low ... • Immunologic Workup ... 60-80% - Low ... #sle #comparison
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Positive in 60-80% of cases ... 60-80% - Low ... Management #Summary #rheumatology
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
- Differential ... Diagnosis Algorithm ... Osmotic diuresis (see ... mannitol, glucosuria Low ... loss • Watery Diarrhea
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Diagnosis Algorithm ... • Burns • Diarrhea ... JAK-2 Positive - Low ... #Causes #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Diagnosis Algorithm ... Better call hematology ... levels: realllly low ... #workup #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Autoimmune Vasculitis (lupus ... deficiency Work ... #Causes #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... • Complement (Low ... vasculitis, and SLE
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... • Immunologic Workup ... in >90% - Low ... Discontinuation of causal ... #DIL #rheumatology
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