16 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... lupus erythematosus ... (SLE), Systemic ... ), Systemic Sclerosis ... rheumatology #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... malignancies, Multiple sclerosis ... #Erythematosus ... autoantibodies #signs ... #symptoms #mimickers
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Aseptic necrosis of hip ... Thrombocytopenia #Lupus #SLE ... #systemic #erythematosus ... #signs #symptoms
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... lupus erythematosus ... disease • Multiple sclerosis ... BEE #Syndromes #neurology ... #inflammatory #differential
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... Constipation, Diarrhea ... Signs and symptoms ... objective evidence of neurologic ... • Acute: - IV
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... and signs below ... Behcet disease - SLE ... , Scleroderma, Systemic ... disorders #diagnosis #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
to Headaches - Differential ... history of cancer, HIV ... pupil (AACG) • Systemic ... symptoms and signs ... Diagnosis #Algorithm #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
lupus erythematosus ... Symptoms (Sx) in ... , particularly scleritis ... purpura: strong sign ... vasculitis, and SLE
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Behcet Disease - Systemic ... Lupus Erythematosus ... syndrome (bulbar symptoms ... Rhombencephalitis #Differential ... Diagnosis #Causes #Neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the nervous system ... fasciculations Common Symptoms ... conditions listed in differential ... motor neurons - IV ... #neurology #diagnosis