22 results
Causes of Pediatric Diarrhea - Differential Diagnosis Algorithm
Infectious:
 • Viral
 • Bacterial
 • Parasitic
Malabsorption:
 • Lactase
Cystic Fibrosis • Celiac ... Disease • Primary ... Inflammatory Bowel Disease ... • Short Bowel Syndrome ... Irritable Bowel Syndrome
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
negative with IgA deficiency ... patients with IgA deficiency ... patients with IgA deficiency ... or HLA-DQ8 - ... Reflects response to treatment
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
• Cushing's Disease ... • GH Deficiency ... • IGF-I Deficiency ... Panhypopituitarism Treatment ... Celiac, IBD) •
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... Cellular immune deficiency ... Unknown cause Treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... Clinical Presentation ... Fever is the main clinical ... • HLH Labs: ... Treatment: • Corticosteroids
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Clinical Findings ... initial phase of the disease ... presentation of Thiamine deficiency ... Encephalopathy Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... age, however the disease ... • Bicytopenia Treatment ... diagnosis #management #treatment
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... due to chronic disease ... Palpitations • Diarrhea ... • Vitamin D deficiency ... hyperparathyroidism Treatment
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... , Chronic diarrhoea ... , Short bowel syndrome ... dental fixatives, Treatment ... drkeithsiau #Copper #Deficiency
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Acute hemolysis, deficiency ... Rebound effect from treatment ... Vasculitides, IBD, Celiac ... disease, Kawasaki ... , Nephrotic syndrome