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management hematology neurology differential hemeonc barre chronic guillain hemophagocytic leukemia lymphocytic lymphohistiocytosis pathophysiology rheumatology signs syndromes acromegaly acute algorithm anemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Diagnosis: • ... microglobulin Treatment ... #workup #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... symptoms can mimic ... Low or absent NK cell ... • Bicytopenia Treatment
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... minimal tumor burden Diagnosis ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... hematology #hemeonc #diagnosis
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS) Clinical features all: fever > 101.3 F most: oxygen
infection (PIMS-TS) Clinical ... features all: ... abdominal pain, diarrhea ... #coronavirus #diagnosis ... #Signs #Symptoms
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... → no immediate treatment ... ± tocilizumab; call ... oncology early ... #HemeOnc #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... hyperinflammatory syndrome ... with the HLH syndrome ... Clinical Presentation ... Common Signs and Symptoms
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... : >3 symptoms, or ... management #hematology #oncology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Clinical ... arrythmias • Other: Diarrhea ... Guillain-Barre Diagnosis ... #diagnosis #management ... #treatment #neurology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Visual or auditory symptoms ... conjunction with symptoms ... and treatment can ... nasal squamous cell ... MRI lesions and clinical
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