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diagnosis differential workup anesthesia anesthesiology autoimmune checklist dermatology hyperthermia myositis product symptoms systemic vasculitis algorithm antimda5 antimda5dm antinxp2 antinxp2dm arteritis
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
- Heliotrope sign ... or shawl sign ... - Gottron's sign ... scale - Holster sign ... #Diagnosis #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... onset [33-74%] • Blood ... #rheumatology #
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Dermatomyositis ... heliotrope rash, Shaw sign ... , holster sign, ... Myositis #diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... Eosinophilia, 500-1,500 cells ... allergy, drug reaction ... organ-specific signs ... Differential #diagnosis #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies Dermatomyositis ... heliotrope, shawl sign ... diagnosis #comparison #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Related Acute Lung ... potassium from lysed cells ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
common immune reaction ... Related Acute Lung ... potassium from lysed cells ... Transfusions #diagnosis #management ... #hematology #reactions
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... Non-small-cell lung ... #diagnosis #management ... #rheumatology #
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
urological device • Blood ... transfusion • Allergic reaction ... hyperthermia crisis (late sign ... • Intracranial blood ... Checklist #Diagnosis #Management
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