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diagnosis differential symptoms systemic erythematosus lupus vasculitis antinxp2 antinxp2dm autoantibodies cabcde cardiology classification clinical comparison constrictive dermatology dermatomyositis echocardiogram hemeonc
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... heliotrope rash, Shaw sign ... , holster sign, ... Can also see mechanics ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... effusion, Restrictive lung ... Glomerulonephritis Myositis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
heliotrope, shawl sign ... exclusion Necrotizing Autoimmune ... Myositis • Onset ... Inclusion Body Myositis ... diagnosis #comparison #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... skin thickening Signs ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
anemia 4% - Myositis ... 4% - Lung involvement ... 3% SLE-Related ... autoantibodies #signs ... #differential #rheumatology
Constrictive Pericarditis on Echocardiogram A 55-year-old female marathon runner presents to clinic w/ 6-months of worsening breathlessness
She had gained 15 ... ASA, Kussmaul's sign ... edema, and clear lungs ... Echocardiogram #a4c ... #pocus #clinical
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 Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... #rheumatology #
Pediatric Trauma Primary Survey: C-ABCDE C - Catastrophic Bleeding - Life-threatening hemorrhage • Apply direct pressure/compression bandage
Apnea/poor effort, Signs ... Binder) • Use POCUS ... ↓ BP is a late sign ... normalized vital signs ... Survey #CABCDE #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Conjunctivitis, mucositis ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology
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