81 results
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
- Heliotrope sign ... or shawl sign ... - Gottron's sign ... - Interstitial lung ... Dermatomyositis #Diagnosis #Rheumatology
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... Manifestations and Management ... #Diagnosis #Management ... #Hematology #SickleCell ... Manifestations #Workup
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... Eosinophilia, 500-1,500 cells ... /µL Workup • Screen ... organ-specific signs ... Differential #diagnosis #hematology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw sign ... , holster sign, ... Myositis #diagnosis #rheumatology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Lung, Bladder, Colon ... pancytopenia, blast cells ... Algorithm #Causes #Hematology
Management of adult IgA Vasculitis (Henoch-Schönlein purpura) - Treatment algorithm for the management of IgAV patients
Management of adult ... algorithm for the management ... presentation and the long-term ... agents improved long-term ... #Treatment #Rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... (interstitial lung ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
biliary, renal, lung ... increased IgG4+ cells ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... anti-NXP2 Abs Lung ... Dermatomyositis #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... = funny-shaped cells ... acute leukemia Management ... MDS #Diagnosis #Management ... #treatment #hematology