906 results
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
Rigors And Bacteremia ... pathogen (e.g., bacteria ... in identifying bacteremia ... PATHOPHYSIOLOGY: ... #Pathophysiology
Non-Infective Endocarditis - Pathophysiology
Non-infective Endocarditis Pathophysiology:
 • Valves usually undamaged - Etiology poorly understood but thought
Endocarditis - Pathophysiology ... Non-infective Endocarditis Pathophysiology ... endothelium is common → Bacteria ... over clusters of bacteria ... NBTE #Marantic #pathophysiology
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Sulfatase enzyme (bacteria ... Syndrome #PUBS #pathophysiology
Lower Urinary Tract Infections: Complications
 - Infection damages the urinary tract epithelium causing fibroblast proliferation and
epithelial barrier -> Bacteria ... - In males, bacteria ... Urease-producing bacteria ... UrinaryTractInfection #LUTI #Pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
susceptibility to bacteremia ... => • Bacteria ... stiffness • Bacteria ... C5C9Deficiency #Complement #pathophysiology
Gonorrhea: Pathophysiology

 - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
Gonorrhea: Pathophysiology ... Immediate transfer of bacteria ... cell surface -> Bacteria ... proteins and LPS on bacteria ... #Gonorrhea #Pathophysiology
Lemierre’s Syndrome - Pathophysiology

Lemierre’s is an infectious thrombophlebitis of the internal jugular vein.

 - It starts
Lemierre’s Syndrome - Pathophysiology ... patient becomes bacteremic ... Lemierres #Syndrome #Pathophysiology
Metabolic Pathways of Purple Urine Bag Syndrome: Adopted from chart originally published in Purple Urine Bag
Bacteria commonly ... #Pathophysiology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
culture proven bacteremia ... culture proven bacteremia ... culture proven bacteremia ... patients with bacteremia ... CBC #hematology #pathophysiology
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen Pathophysiology ... EXOGENOUS PYROGEN • Bacteria ... Fever #Fever #Pathophysiology