75 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic Anemia ... (AIHA) Pathophysiology ... or negative - Smear ... C3 positive - Smear ... #Pathophysiology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... develop leukostasis syndrome ... - infiltrates (anemia ... • Peripheral smear ... • Tumor lysis syndrome
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Peripheral smear ... • Neutropenia, anemia ... • Richter’s Syndrome ... • Sezary syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... cytopenias (usually anemia ... transformation to acute leukemia ... Myelodysplastic #Syndrome
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... promyelocytic leukemia ... peripheral blood smear ... acute myeloid leukemia ... BloodSmear #Blood #Smear
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... • Peripheral smear ... #Lymphocytic #Leukemia ... hemeonc #diagnosis #management
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... Plasmapheresis - Leukemia ... Hydroxyurea - Leukemia ... Hyperviscosity #Syndrome ... Diagnosis #Treatment #Management
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... C3d • Blood smear ... Autoimmune #Hemolytic #Anemia ... #diagnosis #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... • Aplastic Anemia ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Peripheral blood smear
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Cancer: • Leukemia