36 results
diagnosis differential hematology management oncology causes classification algorithm leukemia chronic clinical fever hemeonc hemolysis infectiousdiseases lactate lymphocytic peripheral refeeding signs
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Peripheral blood smear ... anemia • Hypochromic ... anemia (TTP, HUS ... #Anemia #Differential
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Megaloblastic Anemia ... anemia (e.g. ... anemia Sickled ... disease Bite cells ... interpretation #clinical #anemia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... ) - HELLP syndrome ... uremic syndrome ... ) (e.g. lupus, CLL ... diagnosis #hematology #anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... uremic syndrome
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... • Symptoms of anemia ... anemia • Cold ... IgM) • Blood smear ... #hemolytic #anemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell ... anemia, Thalassemias ... Peripheral Blood Smear
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
diarrhoea, Short bowel syndrome ... dental fixatives, Treatment ... • Nutritional: ... /jejunal nutrition ... Haematological: Anaemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... extramedullary disease ... - infiltrates (anemia ... • Peripheral smear ... • Tumor lysis syndrome
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis ... Nutritional
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
, sickle cell disease ... anemia, PNH, immune ... - Pernicious anemia ... • Tumor lysis syndrome ... polyangiitis • Behçet's syndrome
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