24 results
Since these risk factors are numerous and have different effects on the malignancy risk, it is
effects on the malignancy ... probability of malignancy ... [8](Table). ... #Diagnosis #EBM
Size
A solitary pulmonary nodule (SPN) is defined as a single intraparenchymal lesion less than 3 cm
cm are usually malignant ... either benign or malignant ... the chance of malignancy ... listed in the table ... #EBM #Radiology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Bacterial • Viral (EBV ... Infiltrative - Non-Malignant ... Infiltrative - Malignant ... Algorithm #Causes #Hematology
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG)

SAAG ≥ 1.1:
 • Cirrhosis
 • Portal
Differential Diagnosis Table ... Nephrotic syndrome • Malignancy ... Differential #Diagnosis #Table ... Gradient #SAAG #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
concerning for malignancy ... → Refer to hematology ... workup, including BM ... • Nonmalignant hematologic ... treatment • Malignancy
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
most common) - Malignancy ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Body Myositis (IBM ... clinical #diagnosis #rheumatology ... #table
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Viral: HIV, HCV, EBV ... infiltration: malignancy ... Diagnosis #Framework #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
C, A, E, B, D, EBV ... • Obstructive: Malignancy ... Choledocholithiasis, Stricture, Malignancy ... Acute #algorithm #hepatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Systemic disease - Malignancy ... HSV, Varicella, EBV ... dislocation Malignant ... Effusions: - Hematologic ... Osteochondroma Hematologic