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diagnosis management differential chronic cll lymphocytic myelodysplastic treatment aplastic cancer causes ckd dermatology erythematosus hemeonc hemodialysis leukemoid leukocytosis lupus monoclonal
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • Neutropenia, anemia ... leukemia #CLL ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... transformation to acute leukemia ... Management #treatment #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
marrow • Mature B-cell ... involvement • T-cell ... - infiltrates (anemia ... -> Invade Skin: ... #Hematology #Oncology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... Differential Diagnosis Algorithm ... carcinoma • Basal ... • Bleomycin Hematologic ... Anemia • Thalessemia
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
hepatomegaly • Labs: anemia ... predominant immature cells ... Matthew Ho, MD ... #hematology #WBC ... #Leukemoid
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... Transformation to large cell ... marrow failure with anemia ... Lauren Banaszak, MD ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... myelodysplastic syndrome (MDS ... virus (EBV) • Leukemia ... Hypocellular/Hypoplastic MDS ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... Syndromes #diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Angioimmunoblastic T-cell ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell ... Hodgkin lymphoma and leukemia
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