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hematology oncology differential management classification disorders leukemia lymphocytic blood cell hemeonc hodgkins lymphoma lymphoproliferative markers mds myelodysplasia myelodysplastic nonhodgkin pathophysiology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Diagnosis: • ... microglobulin Treatment ... #workup #oncology ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... - CD7, CD3 Chronic ... or λ), Smudge Cells ... Amy Chung, MD, MSc ... #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... Responsive to Treatment ... Amy Chung, MD, MSc ... #Diagnosis #NonHodgkin
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... • Infections: Chronic ... #Algorithm #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Workup: • Full ... lymph node biopsy (diagnostic ... Treatment • Early ... #diagnosis #classification
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... lymphoma (Richter ... #hemeonc #diagnosis
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... Too many cells in ... Better call hematology ... normal/high - Chronic ... #Algorithm #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... phenomenon (16%) MSK ... • B cell lymphoma ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... EMD myeloma Diagnostic ... Bone marrow Treatment ... • Non-Hodgkin Lymphoma ... #Workup #Hematology
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