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hematology management algorithm classification differential anesthesia anesthesiology causes checklist chronic cll diffuse disorders emergencies hemeonc leukemia lymphadenopathy lymphoma lymphomas lymphoproliferative
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can infiltrate ... smear: Smudge cells ... or basket cells ... microglobulin Treatment ... #workup #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Reed-Sternberg Cells ... Biopsy • Hodgkin's ... Lymphadenopathy #LAD ... Causes #Hematology #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... cells. ... Workup: • Full ... Lymphoma Treatment ... classification #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Algorithm Hodgkin ... Reed-Sternberg (RS) Cells ... - 5% RS cells absent ... (LP) tumour B cells ... Amy Chung, MD, MSc
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
aggregate foci (>50 cells ... aggregate) of CD4 T cells ... , B cells, and plasma ... cells around salivary ... phenomenon (16%) MSK
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... compounds, alcohol, lead ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia Tachycardia in theatre is often due to inadequate depth
Intraoperative Tachycardia ... remember to tailor treatment ... OR ventilator bellows ... #Checklist #Diagnosis ... #Management #Workup
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... full infectious work-up ... days → add fungal work-up ... “big & sticky” cells ... #HemeOnc #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
arises from plasma cells ... from the plasma cells ... monoclonal plasma cells ... clonal plasma cells ... #Diagnosis #Workup
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