12 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... Microangiopathic hemolytic ... #Smear #Analysis ... #hematology #microscopy
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... polychromatophilic cells ... #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Diagnostic Criteria for Scleroderma Renal Crisis 

1. New onset blood pressure >150/85 mm Hg OR increase
Microangiopathic hemolytic ... anemia - Findings ... hematuria on urine ... cells on urine ... microscopy -
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... : Acute blood loss ... , Acute hemolysis ... , deficiency anemia ... syndrome, POEMS • Reaction
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... flank pain, dark urine ... Blood products contain ... potassium from lysed cells ... diagnosis #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
flank pain, dark urine ... Blood products contain ... potassium from lysed cells ... of transfused products ... diagnosis #management #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
AIHA, Transfusion reactions ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal ... Differential #Diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
smear - RBC agglutination ... sensitize red blood ... cells (RBCs) at ... passage of red-brown urine ... #anemia #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Fibrin degradation products ... of Peripheral blood ... smear - Shows schistocytes ... anemia Indirect ... Diagnosis #Workup #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... abnormal under the microscope ... abnormal under a microscope ... smear • Bone marrow ... Syndromes #diagnosis #hematology