23 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
peripheral-blood smear ... revealed 25% plasma cells ... Clinical #HONC #Derm ... PlasmaCell #Leukemia #Smear ... #NEJM
African Trypanosomiasis - The examination was notable for the two erythematous lesions, each measuring 3 to
peripheral-blood smear ... B) #Clinical #Derm ... #Pathology #Smear ... TrypanosomaBrucei #NEJM
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
used on a long-term ... , principal cells ... and intercalated cells ... #Pathophysiology ... NephronRemodeling #NEJM
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
peripheral-blood smear ... acanthocytes (or spur cells ... Spur cells acquire ... #NEJM #clinical ... peripheral #blood #smear
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... -> Tissue injury ... Pancarditis and valvular injury ... RheumaticFever #pathophysiology
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood cells ... schizocytes, these cells ... shapes of red cells ... a more generic term ... BloodSmear #Blood #Smear
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
possible vascular injury ... • Vertical Shear ... (VS) - Axial shear ... - Type 1 or 2 injury ... complications #pathophysiology
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
spleen in which red cells ... between endothelial cells ... #Pathophysiology ... HereditarySpherocytosis #NEJM
Pathogenesis of meningitis 

Risk factors for pathogen entry include immunocompromised state (HIV positive, cancer, chemotherapy patients,
), and cranial injury ... Immune cells and ... endothelial cells ... endothelial cells ... #Meningitis #Pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
causes direct injury ... vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology