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ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Dose Comparison ... for better pre-dose ... #Dosing #Conversion ... #PrimaryCare #Comparison ... #Table
Angiotensin Receptor Blocker (ARB) Antihypertensive Dose Comparison

#Pharmacology #Angiotensin #Receptor #Blocker #ARB #Conversion #Table #Dose #Dosages

** GrepMed
Angiotensin Receptor Blocker ... Antihypertensive Dose ... Comparison # ... #ARB #Conversion ... #Table #Dose #Dosages
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Hypokalemia, Erectile ... higher risk of hyperkalemia ... (ACEI, ARB, diabetes ... statins, digoxin) Beta ... contraindications #table
Angiotensin Receptor Blockers 
Recommended Dose Conversions 

Valsartan 
Irbesartan 
Losartan 
Olmesartan 
Telmisartan 
Candesartan 
Azilsartan 
Eprosartan 

A few
Angiotensin Receptor Blockers ... Conversions ... cough compared to ACEI's ... Angiotensin #Receptor #Blockers ... #Table #Dosing
Atrial Fibrillation RVR - Medications
Diltiazem
 • Preferred in patients with chronic lung such as Asthma and
of or increased doses ... rate control when beta-blockers ... conjunction with beta-blockers ... management #treatment #comparison ... #table
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... bradycardia, AV blocks ... -2 hours Dose ... ~2 hours Dose
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Enzyme Inhibitors (ACEIs ... increased bleed risk Beta-Blockers ... Decreases effects of beta-blockers ... Licorice - Causes hypokalemia ... pharmacology #DDI #table
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... Aldosterone • ENaC blockers ... Aldosterone • ACEi ... nephropathy • Beta
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Medications: K+, ACEi ... ARBs, NSAIDs, β-blockers ... Elimination (see Table ... Transient, repeat dose