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diagnosis differential cardiology hyperkalemia hypokalemia nephrology pharmacology antiarrhythmics hematology potassium alkaline alp anemia anesthesia anesthesiology bradycardia checklist clinical clinicopathology digoxin
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... 2 - Beta Blockers ... alpha & beta adrenergic ... #Pharmacology #Classification ... #Classes #pathophysiology
The Diagnostic Approach to Hyperkalemia Drugs - Amiloride - Spironolactone - Triamterene - Trimethoprim - Pentamidine -
inhibitors Other causes ... transplant - SLE High ... Ketoconazole Low ... - NSAlDs - Beta-Blockers ... #differential #causes
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... cells: Insulin, Beta-Agonist ... #causes #potassium ... #low #pathophysiology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Vaughan Williams Classification ... 2 - Beta Blockers ... alpha & beta adrenergic ... #Pharmacology #Classification ... #Classes #pathophysiology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... • ENaC blockers ... nephropathy • Beta ... #Causes
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Low Mean Corpuscular ... Chronic Infection) High ... #Anemia #MCV #Classification ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
are present • Classic ... B-Cell ~90% • Low ... age range • High ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm Decreased intake (rare cause in isolation) GI loss - Urine loss
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... • Insulin • Beta ... Differential #Diagnosis #Algorithm ... #Causes
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... fractures of feet, thigh ... collection with EDTA Pathophysiology ... pyrophosphate) blocks ... Phosphatase: • Other causes
Intraoperative Bradycardia - Guidelines for Crises in Anaesthesia Bradycardia in theatre should not be treated as
Check fresh gas flow ... Consider known drug causes ... Also consider: high ... toxicity (→ 3-10); beta-blocker ... calcium channel blocker
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