15 results
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... organic acids and bases ... Nephron #Segments #Function ... #Pathophysiology ... #Tubules #Table
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
- Anorexia GI Losses ... Differential #Diagnosis #Low ... #Potassium #Table ... #Classification ... #Causes
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... decreased iron absorption ... with TSAT <20% (functional ... endpoint of all-cause
In order to better classify heart failure, the American College of Cardiology Foundation and the American
Heart Association functional ... class, based solely ... describe the current functional ... But now the ACC/ ... #Stages #Classes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Excessive GI losses ... Differential #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... Strong Blockade, Slow ... of phase 4 to slow ... #Pharmacology #Classification ... #Classes #pathophysiology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Definition: • Functional ... Pathophysiology: ... Exclude other AKI causes ... Classification: ... essential in all cases
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Most cases diagnosed ... severe mobility/functional ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... has good renal function ... produces them when low ... anion gap until it closes ... DiabeticKetoacidosis #DKA #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
open leading to slow ... Vaughan Williams Classification ... of phase 4 to slow ... #Pharmacology #Classification ... #Classes #pathophysiology